Leading articles MMR vaccine and allergy

Leading articles MMR vaccine and allergy

Leading articles MMR vaccine and allergy

MMR vaccine and allergy Live measles and mumps vaccine viruses are cultured in chick embryo fibroblasts and may contain minute amounts of egg related antigens. 1–3 In view of this, there has been a longstanding debate on the safety of these vaccines in children with severe allergic reactions to egg. Initially it was believed that such children could safely receive the vaccine; Kamin et al in 19...

Successful administration of measles-rubella-mumps vaccine by graded challenge in a case with anaphylaxis after prior vaccination.

Egg allergy is one of the most common food allergies during childhood along with cow's milk allergy. The measles-mumpsrubella (MMR) vaccine is included in the pediatric immunization schedule and contains egg protein. The currently accepted opinion is that the MMR vaccination should be done in a single dose under medical observation in patients with egg allergy. Although it is reported that the ...

Recommendations for administering the triple viral vaccine and antiinfluenza vaccine in patients with egg allergy.

Actually, food allergy is an emerging pathology; and egg allergy is the most frequent in childhood. The recommendations for measles, mumps and rubella (MMR) and influenza vaccination are increasing each year. This implementation increases the exposure of patients with egg allergy to such vaccines. In Spain, since 2004 the only available vaccine for MMR is grown in cultures of fibroblast from ch...

Investigation of the Relationship between the Residual Moisture and Thermal Stability of Lyophilized MMR Vaccine

Background and Aims: The safe, potent and effective live vaccines against Measles, Mumps and Rubella as important childhood diseases have been available for several decades. Several factors can affect the thermal stability of lyophilized vaccine. Methods: In this study, the effect of residual moisture on thermal stability of 61 batches of MMR vaccine was investigated using an accelerated ...